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Updated: Jun 17, 2026

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
Published on: December 6, 2024
Parameters for coronary plaque vulnerability assessed with multidetector computed tomography and intracoronary
Francesca Pugliese1, Willem B Meijboom, Jurgen Ligthart
1Department of Radiology, The Netherlands Azienda Ospedaliero-Universitaria di Parma, Non-Invasive Cardiovascular Imaging, Piastra Tecnica, Piano 0, Via Gramsci 14, 43100 Parma, Italy.
Abstract:
In the absence of a fixed relationship between plaque vulnerability and flow-limiting stenosis, alternative morphological expressions exist that could predict the liability of coronary lesions to rapidly progress or rupture, causing acute coronary syndromes. Modern multidetector computed tomography technology is capable of noninvasively detecting lesion location, attenuation, remodeling and calcification pattern, which may be considered as surrogate morphological markers of vulnerability and could contribute to increase the prognostic value of individual coronary plaque burden.
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