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Published on: December 9, 2022
The prepare pilot RCT of home-based progressive resistance exercises for venous leg ulcers
1School of Nursing University of Auckland, New Zealand. ajull2@auckland .ac.nz
Home-based progressive resistance exercise is feasible for venous leg ulcer patients. While calf muscle pump function improved, its impact on ulcer healing needs more study.
Area of Science:
- Vascular Medicine
- Exercise Physiology
- Wound Care
Background:
- Venous leg ulcers (VLUs) are common and associated with impaired calf muscle pump (CMP) function.
- Improving CMP function may enhance VLU healing, but effective community-based interventions are needed.
Purpose of the Study:
- To assess the feasibility of a home-based progressive resistance exercise (PRE) program to improve CMP function in patients with VLUs.
- To evaluate the impact of PRE on CMP function and VLU healing parameters.
Main Methods:
- A 12-week randomized controlled trial comparing PRE (heel raises) plus compression to usual care plus compression.
- Stratified randomization by ulcer duration and size.
- Calf muscle pump function assessed by air plethysmography; ulcer parameters measured with SilhouetteMobile.
Main Results:
- Forty participants were randomized. The PRE group showed significantly greater improvement in calf ejection fraction (18.5% difference, p<0.05).
- Adherence to exercise was high (81%) with no increase in adverse events.
- No significant differences were observed in ulcer healing rates or time to healing between groups.
Conclusions:
- A community-based randomized trial of home-based PRE for VLU patients is feasible.
- The exercise program effectively improved calf ejection fraction.
- Further research is required to determine the effect of this exercise intervention on VLU healing.
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