Related Experiment Video
Updated: Jun 17, 2026
Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Retrospective analysis of thrombolysis therapy for 64 cases of acute myocardial infarction with elevated ST segment
Xiao-xia Fu1, Wen-jian Xiao, Jian Lu
1The First Traditional Chinese Medicine Hospital of Zhanjiang City, Guangdong, China. Fu_tiger@sina.com
Insights
Xueshuantong Injection (XST) improved cardiac function and reduced cardiac events in acute myocardial infarction (AMI) patients post-reperfusion. This integrative therapy offers cardiac protection following thrombolysis.
Area of Science:
- Cardiology
- Integrative Medicine
- Pharmacology
Background:
- Acute myocardial infarction (AMI) with ST-segment elevation requires prompt reperfusion therapy.
- Integrative therapies are increasingly explored to enhance outcomes in cardiovascular diseases.
Purpose of the Study:
- To investigate the cardiac protective effects of Xueshuantong Injection (XST) as an adjunct therapy in patients with AMI after reperfusion.
- To evaluate the impact of XST on cardiac function and clinical outcomes.
Main Methods:
- A retrospective analysis of 64 AMI patients treated with thrombolysis.
- Comparison between a control group (urokinase) and a treated group (urokinase + XST).
- Monitoring of cardiac enzymes, echocardiographic parameters, and 6-month incidence of cardiac events.
Main Results:
- No significant difference in peak cardiac enzyme levels or their appearance time between groups.
- Significant improvements in heart function parameters at day 7 and 14 in the XST-treated group compared to controls (P<0.05, P<0.01).
- Reduced incidence of cardiac events in the XST group during the 6-month follow-up (P<0.05).
Conclusions:
- Xueshuantong Injection (XST) demonstrates a significant cardiac protective effect in AMI patients post-reperfusion.
- XST improves cardiac function and reduces adverse cardiac events when used adjunctively with thrombolysis.
- This study supports the role of XST in the management of acute myocardial infarction.
Objective:
To explore the cardiac protective effect of integrative therapy in acute myocardial infarction (AMI) with elevated ST segment after reperfusion.
Methods:
Sixty-four AMI patients who having received decimalization by thrombolysis were assigned to two groups by retrospective analysis, 36 patients in the treated group and 28 in the control group. Both were treated by intravenous administering of urokinase for thrombolysis, and to the treated group, intravenous dripping of Xueshuantong Injection (, XST) was added. Serum levels of myocardial associated enzymes were monitored before treatment and at various time points after thrombolysis, and the heart function parameters were detected with color echocardiography before treatment and on the 7th and 14th day of treatment. The patients were followed up for 6 months to observe the incidence of cardiac events.
Results:
The differences between groups at the peak and peak appearing time of creatine kinase and creatine kinase isoenzyme were not significant. All the heart function parameters on the 7th and 14th day in the treated group were improved and superior to those at the corresponding time points in the control group (P<0.05, P<0.01). Incidence of some heart events in the treated group within the 6-month follow-up period was lesser than that in the control group (P<0.05).
Conclusion:
XST Injection could provide effective protection for the heart after reperfusion.
Related Concept Videos
01:30Acute Coronary Syndrome I: Introduction
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations