Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

Imaging Studies IV: Magnetic Resonance Imaging

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluation of a modular all-in-one high-resolution PET detector and readout electronics setup.

Physics in medicine and biology·2023

Same author

Design and performance simulation studies of a breast PET insert integrable into a clinical whole-body PET/MRI scanner.

Physics in medicine and biology·2023

Same author

Automated lung cancer assessment on 18F-PET/CT using Retina U-Net and anatomical region segmentation.

European radiology·2023

Same author

Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14-16, 2018; Vienna, Austria.

Molecular imaging and biology·2019

Same author

Dual layer doI detector modules for a dedicated mouse brain PET/MRI.

Physics in medicine and biology·2019

Same author

Optimization, evaluation and calibration of a cross-strip DOI detector.

Physics in medicine and biology·2018

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

Combined PET/MR imaging--technology and applications.

H F Wehrl¹, A W Sauter, M S Judenhofer

¹University of Tuebingen, Laboratory for Preclinical Imaging and Imaging Technology of the Werner Siemens-Foundation, Roentgenweg 13, 72076 Tuebingen, Germany.

Technology in Cancer Research & Treatment

|January 20, 2010

Summary

Positron emission tomography (PET) combined with magnetic resonance imaging (MRI) offers advanced imaging without extra radiation, superior soft tissue contrast, and diverse tracer applications, revolutionizing oncology, neurology, and cardiology research and clinical practice.

More Related Videos

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice

Published on: October 25, 2024

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

Related Experiment Videos

Last Updated: Jun 17, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice

Published on: October 25, 2024

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

Area of Science:

Biomedical imaging
Medical physics
Radiology

Background:

Conventional imaging modalities have limitations.
Combined PET/MR systems offer synergistic advantages.
Technical challenges in integrating PET and MR exist.

Purpose of the Study:

To explore the advantages of combined PET/MR imaging.
To discuss technical challenges and solutions in PET/MR system design.
To highlight the applications of PET/MR in oncology, neurology, and cardiology.

Main Methods:

Integration of PET components within an MR system.
Development of novel detector technologies (e.g., semiconductor light detectors).
Exploration of technical solutions like optical fibers to mitigate MR interference.

Main Results:

PET/MR provides enhanced soft tissue contrast and no additional radiation dose.
Successful implementation of PET/MR systems addressing technical challenges.
Demonstrated applications in visualizing key cancer processes: apoptosis resistance, angiogenesis, proliferation, and metastasis.

Conclusions:

Combined PET/MR imaging presents significant advantages over conventional methods.
Technical hurdles in PET/MR system design are being overcome.
PET/MR holds immense potential for simultaneous multifunctional and anatomical imaging in research and clinical settings.