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Published on: February 1, 2016
An X-Ray computed tomography/positron emission tomography system designed specifically for breast imaging
John M Boone1, Kai Yang, George W Burkett
1Department of Radiology Engineering University of California, Davis UC Davis Medical Center 4860 Y Street, ACC Suite 3100 Sacramento, CA 95817, USA. john.boone@ucdmc.ucdavis.edu
Breast CT offers a promising alternative to mammography for breast cancer imaging. This advanced computed tomography technology is well-suited for breast imaging, reducing artifacts and improving visualization for interventional procedures.
Area of Science:
- Radiology
- Medical Imaging
- Biomedical Engineering
Background:
- Mammography has been a standard for breast cancer screening for over 30 years.
- Advancements in digital detectors have improved mammography, while other imaging modalities like computed tomography (CT) have also evolved.
- Large field-of-view flat panel detectors have facilitated the development of specialized CT applications, including breast CT.
Purpose of the Study:
- To explore the potential of cone beam CT for breast imaging.
- To design a novel breast CT system for image-guided interventional procedures.
- To prepare for multi-institutional clinical trials to assess the role of breast CT in clinical practice.
Main Methods:
- Utilizing cone beam geometry for CT imaging of the breast.
- Leveraging the anatomical characteristics of the breast (lack of bone, natural tapering) to minimize CT artifacts.
- Developing a third-generation prototype breast CT system.
Main Results:
- The breast's anatomy is well-suited for cone beam CT, reducing common artifacts.
- The tapering of the breast minimizes X-ray path lengths, further reducing cone beam artifacts.
- A new prototype system is being designed for interventional procedures.
Conclusions:
- Breast CT shows significant potential as an advanced imaging modality.
- The technology is particularly advantageous due to reduced artifacts compared to other CT applications.
- Future clinical trials will establish the role of breast CT in breast imaging and interventions.
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