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Updated: Jun 17, 2026

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
Acute hyperglycaemia and mortality in patients with transient ischaemic attack
Matthew N T Thuy1, Peter J Hand
1Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria, Australia. matthew.thuy@gmail.com
Abstract:
Acute hyperglycaemia is associated with poorer outcome in stroke, however limited evidence is available regarding its association with transient ischaemic attack (TIA). This study aimed to determine the association between acute hyperglycaemia and mortality in 194 patients with TIA. Mortality data were obtained from a state-wide death registry. No significant association was identified with either multivariate Cox regression (p=0.65) or Kaplan-Meier analysis (p=0.85). Because of the low death rate, a larger sample is required to reliably exclude an association. Univariate analysis identified significantly associated variables, including TIA clinical prediction scores (e.g. ABCD and ABCD2). Multivariate analysis identified age, atrial fibrillation and duration 1 hour as independent significant predictors of mortality.
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