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Related Experiment Video

Updated: Jun 17, 2026

In Vitro Assays to Evaluate the Migration, Invasion, and Proliferation of Immortalized Human First-trimester Trophoblast Cell Lines
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In Vitro Assays to Evaluate the Migration, Invasion, and Proliferation of Immortalized Human First-trimester Trophoblast Cell Lines

Published on: March 5, 2019

Deflazacort.

N Joshi1, K Rajeshwari

  • 1Department of Pediatrics, Maulana Azad Medical College, New Delhi, India.

Journal of Postgraduate Medicine
|January 20, 2010
PubMed
Summary
This summary is machine-generated.

Deflazacort, an alternative oral steroid, shows potential for fewer side effects like osteoporosis and growth issues compared to traditional steroids. However, more research is needed due to limited trials and high cost.

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Last Updated: Jun 17, 2026

In Vitro Assays to Evaluate the Migration, Invasion, and Proliferation of Immortalized Human First-trimester Trophoblast Cell Lines
09:57

In Vitro Assays to Evaluate the Migration, Invasion, and Proliferation of Immortalized Human First-trimester Trophoblast Cell Lines

Published on: March 5, 2019

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

Area of Science:

  • Pediatric pharmacology
  • Clinical immunology

Background:

  • Conventional oral steroids (e.g., prednisolone) are associated with significant adverse effects.
  • There is an ongoing global search for oral steroid alternatives with improved safety profiles.

Purpose of the Study:

  • To evaluate deflazacort as a potential alternative oral steroid with fewer side effects.
  • To review existing data on deflazacort use in pediatric steroid-responsive disorders.

Main Methods:

  • Review of preliminary data and limited randomized trials involving deflazacort.
  • Focus on studies related to Duchenne's muscular dystrophy and other steroid-responsive conditions in children.

Main Results:

  • Preliminary data suggest deflazacort may lead to reduced osteoporosis, growth retardation, and weight gain compared to other steroids.
  • The number of large-scale randomized trials remains limited.

Conclusions:

  • Deflazacort presents a potential alternative to conventional oral steroids in pediatric care.
  • Widespread use of deflazacort in children is not yet recommended due to limited evidence of superiority and high cost.