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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Published on: September 14, 2010

Recognizing Kawasaki disease.

¹IWK Health Centre, Halifax, Nova Scotia.

Paediatrics & Child Health

|January 20, 2010

Summary

This summary is machine-generated.

Kawasaki disease (KD), a common childhood vasculitis, primarily affects children aged 1-3. Recognizing KD is crucial for clinicians, especially in infants and complex fever cases.

Keywords:

Diagnosis Kawasaki disease Treatment Vasculitis

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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Area of Science:

Pediatrics
Rheumatology
Immunology

Background:

Kawasaki disease (KD) is a prevalent systemic vasculitis affecting young children.
It predominantly occurs in children aged one to three years, with a male predominance (1.5:1 ratio).
Incidence rates vary globally, with Japan reporting the highest rates.

Purpose of the Study:

To aid clinicians in recognizing Kawasaki disease in pediatric patients.
To highlight diagnostic challenges, particularly in infants under six months and children with prolonged fever and incomplete criteria.

Main Methods:

This paper is a clinical review aimed at enhancing diagnostic skills.
It focuses on identifying key clinical features and challenging presentations of KD.

Main Results:

Kawasaki disease is rare in infants under six months and children over eight years, but can occur.
Boys are affected more frequently than girls.
Incidence rates are approximately 13/100,000 children under five in Canada, with higher rates in Japan.

Conclusions:

Early and accurate recognition of Kawasaki disease is essential for timely management.
Pediatricians must consider KD in infants and children presenting with prolonged fever, even with atypical or insufficient diagnostic criteria.