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Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

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In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
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Related Experiment Video

Updated: Jun 17, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

e-Health? Clinical information network interest and impediments in a community paediatric setting.

R Cawdron1, J Calder, R M Issenman

  • 1Children's Hospital, Hamilton Health Sciences Centre.

Paediatrics & Child Health
|January 20, 2010
PubMed
Summary

Paediatricians in Ontario showed strong interest in the Central West Ontario Pediatric Information Network (CWPIN). Workplace computer use, not literacy, may influence network adoption by sex.

Keywords:
Clinical information networkIntranetPaediatricsUtilization rates

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Last Updated: Jun 17, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Area of Science:

  • Health Informatics
  • Paediatric Medicine
  • Evidence-Based Practice

Background:

  • Electronic resources can enhance paediatric care efficiency and cost-effectiveness.
  • Barriers to implementing clinical information resources include physician attitudes and system capabilities.

Purpose of the Study:

  • To assess electronic information resource needs of community paediatricians in Ontario.
  • To gauge interest in accessing the proposed Central West Ontario Pediatric Information Network (CWPIN).

Main Methods:

  • A cross-sectional, interviewer-facilitated, structured survey was conducted.
  • The study population comprised paediatricians in community care within the Central West Ontario Health Region.

Main Results:

  • 98% of surveyed paediatricians expressed interest in accessing the CWPIN.
  • High rates of home computer (88%) and internet (81%) use suggest good computer literacy.
  • Workplace computer use differed by sex, potentially impacting network adoption.

Conclusions:

  • Physicians demonstrated significant interest in adopting the CWPIN.
  • Sex-based disparities in workplace computer use, not literacy, may affect network utilization.
  • Attitudes and computer proficiency are unlikely to hinder the implementation of this clinical information resource.