Related Experiment Videos
Partial duplication of the face: case report and review
G D Verdi1, J H Hersh, L J Russell
1Department of Surgery (Plastic and Reconstructive Surgery), University of Louisville School of Medicine, Ky.
Plastic and Reconstructive Surgery
|April 1, 1991
Summary
Facial duplication, a rare congenital condition, was observed to be discordant in identical twins. One twin exhibited significant maxillary and mandibular duplication, alongside other facial anomalies.
Area of Science:
- Medical Genetics
- Developmental Biology
- Craniofacial Surgery
Background:
- Facial duplication is a rare congenital malformation with variable severity.
- Monozygotic twins typically share identical genetic material, making discordance in congenital anomalies noteworthy.
Observation:
- A case of monozygotic twins presenting discordance for facial duplication is described.
- One twin exhibited complete facial duplication, including maxillary and mandibular duplication.
Findings:
- The affected twin presented with ocular hypertelorism, bifid nose, duplicated maxilla, macrostomia, cleft lip, vomer hamartoma, supernumerary teeth, duplicated mandibular teeth, bifid tongue, and floor of mouth hamartoma.
- This case highlights a rare spectrum of craniofacial abnormalities in facial duplication.
Implications:
- Understanding the genetic and environmental factors contributing to discordance in monozygotic twins is crucial.
- Surgical management strategies for complex craniofacial duplication require tailored approaches.
- Further research into the etiology of facial duplication can inform genetic counseling and early intervention.