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Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)
Published on: July 31, 2021
[Change of rubella antibody transferred by mother in infants]
Rui Ma1, Guo-Zhang Xu, Chao Ma
1Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, Zhejiang, China.
Objective:
To Know the antibody level of comparison in maternal-infant pairs and the change of rubella in infants, and to provide scientific basis for controlling congenital rubella syndrome.
Methods:
Newborn, 3, 6, 8, 9-month infant who never had rubella and their mothers were residents in Ningbo of Zhejiang, Harbin of Heilongjiang and Jinan of Shandong were collected as objects. Their serum samples were tested by the method of ELISA.
Results:
The positive rate of Rubella antibody in newborns, 3, 6, 8, 9, were 74.4, 14.9, 3.3, 4.6, 15.0 percent respectively, and GMC were 34.06, 5.42, 1.48, 1.10, 1.83IU/ml respectively. The positive rate and GMC of Rubella antibody in mothers were 71.1 percent and 30.96IU/ml. The correlation coefficient between mother and infant was 0.658.
Conclusion:
Maternal-transferred rubella antibody decreased as the growth of infants. The positive rate of measles antibody was very low in 6 and 8-month, which almost had no protection.
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