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Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging
Published on: January 5, 2015
Activation of fluorescent protein chromophores by encapsulation
Anthony Baldridge1, Shampa R Samanta, Nithyanandhan Jayaraj
1School of Chemistry and Biochemistry, 901 Atlantic Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA.
Journal of the American Chemical Society
|January 21, 2010
Abstract:
Chromophores related to fluorescent proteins, when sequestered into the "octaacid" capsule, recover their fluorescence. The fluorescence recovery is related to the inhibition of torsional motions within the cavity, implicating the single-bond torsion as an important contributor to internal conversion within this important class of chromophores.

