Related Experiment Video
Updated: Jun 16, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
A review of pharmacologic options for previously untreated chronic lymphocytic leukemia
1University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 377, Houston, Texas 77030, USA.
Abstract:
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and has a heterogeneous clinical course. Some patients experience an indolent disease course, which does not require treatment or affect their overall quality of life. Other patients present with symptomatic advanced disease that rapidly progresses and requires therapy. For these patients, chemotherapy is the mainstay of treatment and has undergone significant evolution in the past few decades. From alkylating agents to purine analogs, response rates have greatly improved with new chemotherapy regimens. The development of chemoimmunotherapy regimens has also transformed the treatment of CLL. This article will review front-line treatment options for CLL and discuss the updated National Comprehensive Cancer Network guidelines.
Related Concept Videos
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Psychosis: Goals of Pharmacotherapy
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Treatment Resistant Cancers
Treatment Resistent Cancers
Drug Therapy
Antianxiety Medications

