Related Experiment Video
Updated: Jun 16, 2026

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
Published on: March 6, 2018
Benign prostatic hypertrophy which nonoperative strategies are best?
Michael J Wehle1, Scott W Lisson
1Department of Urology, Mayo Medical School, Jacksonville, FL, 32224, USA. wehle.michael@mayo.edu.
Benign prostatic hypertrophy (BPH) is common in older men. Primary care physicians must understand BPH epidemiology, pathophysiology, and treatments to manage lower urinary tract symptoms and prevent complications.
Area of Science:
- Urology
- Primary Care Medicine
Background:
- Benign prostatic hypertrophy (BPH) is a prevalent condition affecting aging men.
- Lower urinary tract symptoms (LUTS) are a common complaint in primary care settings.
Purpose of the Study:
- To review the epidemiology, pathophysiology, natural history, clinical presentation, and treatment options for BPH.
- To equip primary care physicians with knowledge for managing clinically significant BPH cases.
Main Methods:
- Literature review focusing on BPH.
- Synthesis of information on BPH diagnosis and management.
Main Results:
- BPH affects a significant portion of the aging male population.
- Nonoperative therapies aim to alleviate LUTS and prevent morbidity like urinary retention and renal impairment.
Conclusions:
- Primary care physicians play a crucial role in the early detection and management of BPH.
- Comprehensive understanding of BPH is essential for effective patient care and prevention of serious complications.
Related Concept Videos
Urinary Tract Calculi VI: Surgical Management
Adrenergic Antagonists: Pharmacological Actions of ɑ-Receptor Blockers
α1-blockers: These drugs inhibit α1-adrenoceptors on smooth muscle cells, resulting in vasodilation. This vasodilation lowers blood pressure, making α1-blockers valuable in treating hypertension. Additionally, α1-blockers effectively address urinary obstruction...
Urinary Tract Calculi III: Medical Management
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
