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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:

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Related Experiment Video

Updated: Jun 16, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

What can physicians do about obesity?

R E Andersen1

  • 1Division of Geriatric Medicine and Gerontology, Johns Hopkins School of Medicine, Baltimore, MD, 21224, USA. andersen@jhmi.edu.

The Physician and Sportsmedicine
|January 21, 2010
PubMed
Summary
This summary is machine-generated.

Obesity is a significant health issue. Controlling obesity is crucial for preventing coronary heart disease (CHD) and its related complications.

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An Acupoint Catgut-embedding Therapy for Treating Obesity
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An Acupoint Catgut-embedding Therapy for Treating Obesity

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Last Updated: Jun 16, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
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Multidisciplinary Approach to Obesity Management: A Case Report

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An Acupoint Catgut-embedding Therapy for Treating Obesity
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An Acupoint Catgut-embedding Therapy for Treating Obesity

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Area of Science:

  • Cardiovascular Health
  • Public Health

Background:

  • Obesity is a widespread and serious health concern.
  • The American Heart Association recognized obesity as a major controllable risk factor for coronary heart disease (CHD) in 1998.

Purpose of the Study:

  • To highlight the significance of obesity as a modifiable risk factor for CHD.
  • To emphasize the role of obesity management in preventing cardiovascular mortality and morbidity.

Main Methods:

  • Review of epidemiological data on obesity prevalence.
  • Analysis of established risk factors for coronary heart disease.
  • Inclusion of expert consensus statements from leading cardiovascular organizations.

Main Results:

  • Obesity is identified as a primary, controllable risk factor for CHD.
  • Effective weight management strategies can mitigate CHD risks.

Conclusions:

  • Obesity management is essential for reducing the burden of coronary heart disease.
  • Public health initiatives should prioritize obesity prevention and treatment to improve cardiovascular outcomes.