Related Experiment Video
Updated: Jun 16, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Sun and active patients: preventing acute and cumulative skin damage
1Albert Lea Medical Center, Alberta Lea, MN, 56007, USA.
Abstract:
Damage from long-term, cumulative effects of sun exposure, while slow to develop, can become life-threatening. The cutaneous effects of ultraviolet light include sunburn, photosensitivity, immunosuppression, premature aging, and several types of skin cancer. Clinicians need to know the characteristic appearance of premalignant lesions, basal cell carcinoma, squamous cell carcinoma, and malignant melanoma. Also, patients who are active outdoors need education about sun protection, including avoidance at peak hours, clothing, sunglasses, and sunscreens. Care for sunburn may involve cool compresses, corticosteroid cream, oral antihistamines, and anti-inflammatory drugs.
Related Concept Videos
Mutations
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Acne Infection
Pigmentation
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

