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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

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Related Experiment Video

Updated: Jun 16, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
12:18

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft

Published on: August 8, 2020

Gluing minor skin wounds.

R H Strauss1

  • 1The Physician and Sportsmedicine, Minneapolis, MN, 55435, USA.

The Physician and Sportsmedicine
|January 21, 2010
PubMed
Summary

Cyanoacrylate adhesives, commonly known as super glues, offer rapid bonding for household repairs. While effective, accidental bonding of skin, such as fingers, is a common occurrence requiring specific removal techniques.

Area of Science:

  • Materials Science
  • Consumer Product Chemistry

Background:

  • Cyanoacrylate adhesives, marketed as Super Glue and Krazy Glue, have become ubiquitous in home applications.
  • These adhesives are known for their rapid polymerization and strong bonding capabilities on various substrates.

Purpose of the Study:

  • To highlight the common household use and rapid bonding properties of cyanoacrylate adhesives.
  • To implicitly address the frequent issue of accidental skin bonding associated with these products.

Main Methods:

  • The abstract does not detail specific experimental methods.
  • It relies on general knowledge of cyanoacrylate adhesive properties and common user experiences.

Main Results:

  • Cyanoacrylate glues provide instant bonding for a wide range of materials.

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  • Accidental bonding of skin, specifically digits like the thumb and index finger, is a frequently encountered outcome of their use.

    • Conclusions:

    • Super Glue and Krazy Glue represent significant advancements in adhesive technology for consumers.
    • Users should be aware of the rapid bonding action, including potential for unintended adhesion to skin.