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Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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Insidious illness in active seniors: decoding atypical presentations.

C E Jimenez1, J Caravalho, I Hwang

  • 1Walter Reed Army Medical Center, Washington, DC, 20307, USA.

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Active seniors and older athletes can mask serious medical conditions. Recognizing atypical symptoms is crucial for timely diagnosis and treatment of conditions like heart disease and pneumonia in this population.

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Area of Science:

  • Geriatric Medicine
  • Sports Medicine
  • Internal Medicine

Background:

  • Older athletes and active seniors may present with serious medical issues that lack typical signs and symptoms.
  • Conditions like coronary artery disease, bacterial pneumonia, and peptic ulcer disease can manifest unusually in senior patients.

Purpose of the Study:

  • To highlight the importance of recognizing atypical presentations of common diseases in active older adults.
  • To emphasize the need for heightened clinical suspicion in this demographic.

Main Methods:

  • Case study analysis of an older tennis player, a golfer, and a deep-sea sport fisherman.
  • Review of literature on disease presentation in senior athletes.

Main Results:

  • Illustrates unusual presentations of coronary artery disease, bacterial pneumonia, and peptic ulcer disease in senior patients.
  • Demonstrates how factors like coexisting illnesses, medication use, reduced reserves, altered pain perception, and symptom denial can affect presentation.

Conclusions:

  • Clinicians must maintain alertness for atypical disease manifestations in active senior patients.
  • Prompt treatment can be facilitated by considering the unique physiological and psychological factors influencing symptom perception and reporting in older athletes.