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Related Concept Videos

Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

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Related Experiment Video

Updated: Jun 16, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Managing allergies in active people.

M N Blumenthal1, C Sherman

  • 1Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.

The Physician and Sportsmedicine
|January 21, 2010
PubMed
Summary
This summary is machine-generated.

Exercise doesn't cause allergies, but athletes need special care when allergies arise. Physical activity can worsen hay fever, asthma, and dermatitis, requiring personalized treatment plans.

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Last Updated: Jun 16, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Humanized Mediator Release Assay as a Read-Out for Allergen Potency
10:22

Humanized Mediator Release Assay as a Read-Out for Allergen Potency

Published on: June 29, 2021

Area of Science:

  • Allergy and Immunology
  • Sports Medicine
  • Dermatology

Background:

  • Exercise can exacerbate pre-existing allergies and trigger allergic-like symptoms.
  • Athletes may have increased exposure to environmental allergens and irritants during physical activity.
  • The interaction between exercise, allergens, and irritants complicates diagnosis and management.

Purpose of the Study:

  • To highlight the unique considerations for managing allergies in active individuals.
  • To emphasize the importance of understanding exercise patterns in allergy evaluation.
  • To guide treatment strategies and medication choices for athletic patients with allergies.

Main Methods:

  • Review of existing literature on exercise-induced allergies and allergic conditions.
  • Analysis of the interplay between physical activity, allergens, and irritants.
  • Clinical considerations for diagnosing and treating allergies in athletes.

Main Results:

  • Exercise is not a cause of allergies but can significantly worsen symptoms.
  • Increased exposure to allergens (e.g., pollen) and irritants (e.g., air pollution) during exercise is common.
  • Strenuous activity can mimic allergic reactions, complicating clinical assessment.

Conclusions:

  • Active patients with allergies require tailored management approaches.
  • Individual exercise habits and preferences are crucial for effective allergy treatment in athletes.
  • Personalized strategies are essential for managing allergic conditions in physically active individuals.