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The risk of congestive heart failure is increased in persons with varicose veins
L A Mäkivaara1, T M Ahti, T Luukkaala
1University of Tampere, Tampere School of Public Health, Tampere, Finland. liisa.makivaara@uta.fi
Insights
Individuals with varicose veins face an increased risk of developing congestive heart failure (CHF). This study found a higher incidence of CHF in those with varicose veins, independent of other risk factors.
Area of Science:
- Cardiovascular Epidemiology
- Vascular Medicine
Background:
- Varicose veins are prevalent, yet their link to cardiovascular diseases like congestive heart failure (CHF) remains unclear.
- Understanding this association is crucial for comprehensive patient risk assessment.
Purpose of the Study:
- To investigate the association between varicose veins and the risk of developing congestive heart failure (CHF).
- To determine if varicose veins independently predict CHF incidence.
Main Methods:
- A longitudinal study of 4903 middle-aged Finnish residents.
- Questionnaire-based data collection on varicose veins and CHF prevalence/incidence over five years.
Main Results:
- Higher prevalence of CHF observed in individuals with varicose veins (2.9% vs. 1.9%).
- Significantly increased incidence of CHF in the varicose vein group (4.9 vs. 2.6 per 1000 person-years).
- Multi-adjusted incidence rate ratio for CHF associated with varicose veins was 2.1 (1.1-4.0).
Conclusions:
- Varicose veins are associated with an elevated risk of congestive heart failure.
- This increased risk is not explained by common confounders such as age, sex, hypertension, or arterial disease.
Aim:
Varicose veins are a common condition but their etiology and relationship with other cardiovascular diseases are not well established. The aim of the study was to find out if persons with varicose veins have a higher risk of congestive heart failure (CHF) than persons without varicose veins.
Methods:
The prevalence of CHF at entry and the incidence of CHF during a five-year follow-up period were studied in persons with and without varicose veins. A study was conducted with a questionnaire in a population of 4903 middle-aged residents in Tampere, Finland.
Results:
Marginally higher prevalence of CHF was found in persons with varicose veins than in those without (2.9% vs. 1.9%) with OR 1.6 (1.0-2.3) and sex and age adjusted OR 1.2 (0.8-1.9). The incidence of CHF was higher in subjects with varicose veins than in others (4.9 vs. 2.6 per 1000 person-years) with IDR 1.9 (1.1-2.9) and sex and age adjusted IOR 2.5 (1.4-4.6). The result was further adjusted for body mass index, arterial disease and hypertension; multi-adjusted IOR for the incidence of CHF by varicose veins was 2.1 (1.1-4.0).
Conclusions:
Our longitudinal observation is consistent with the hypothesis that persons with varicose veins have a higher risk of CHF which is not mediated through sex, age, overweight, arterial disease or hypertension.
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