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Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

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Inflammatory Bowel Disease II: Crohn's Disease

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Crohn's disease
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Inflammatory Bowel Disease IV: Clinical Manifestations01:20

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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
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Microscopic colitis in patients presenting with chronic diarrhea.

Vatsala Misra1, S P Misra, Manisha Dwivedi

  • 1Department of Pathology, Moti Lal Nehru Medical College, Allahabad, India.

Indian Journal of Pathology & Microbiology
|January 22, 2010
PubMed
Summary

Microscopic colitis affects 3.7% of patients with chronic watery diarrhea. Consider this diagnosis in patients with normal colonoscopies to ensure proper treatment.

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Area of Science:

  • Gastroenterology
  • Histopathology

Background:

  • Chronic watery diarrhea is a common gastrointestinal complaint.
  • Microscopic colitis is often diagnosed after ruling out other causes.

Purpose of the Study:

  • To determine the prevalence of microscopic colitis in patients with chronic watery diarrhea.
  • To highlight the importance of histopathological examination in diagnosing microscopic colitis.

Main Methods:

  • Colonic biopsies were analyzed from 400 patients with chronic watery diarrhea.
  • Biopsies were stained with hematoxylin and eosin and Masson's trichrome.
  • Histological examination identified collagenous and lymphocytic colitis.

Main Results:

  • Microscopic colitis was found in 3.7% of patients (15/400).
  • Lymphocytic colitis was more common (67%) than collagenous colitis (33%).
  • Most patients (80%) had normal colonoscopy findings.

Conclusions:

  • Microscopic colitis should be considered in patients with chronic watery diarrhea, even with normal colonoscopy.
  • Histopathological analysis of colonic biopsies is crucial for accurate diagnosis.
  • Timely diagnosis of microscopic colitis is essential for appropriate patient management.