Related Experiment Video
Updated: Jun 16, 2026

Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells
Published on: May 11, 2020
Biotransformation of nicotine by microorganism: the case of Pseudomonas spp
Hongjuan Li1, Xuemei Li, Yanqing Duan
1Laboratory for Conservation and Utilization of Bio-Resources, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming 650091, People's Republic of China.
Abstract:
Several bacterial species are capable of using nicotine, the main alkaloid in tobacco plants, as a substrate for growth. The dominant species include members of two genera, Pseudomonas and Arthrobacter. The degradation pathway and genetic structure of nicotine catabolism in Arthrobacter nicotinovorans were recently reviewed (Brandsch Appl Microbiol Biotechnol 69:493-498, 2006). Here, we present up-to-date information on biodegradation of nicotine by Pseudomonas spp. Species in this genus capable of degrading nicotine are summarized and analyzed phylogenetically. Their metabolic intermediates and nicotine degradation-related genes were summarized, and the nicotine-biotransformation pathways were compared and discussed.
Related Concept Videos
Bioremediation
Microbial Bioremediation of Pesticides
Environmental Applications of Microorganisms
Production of Antibiotics
Drug Biotransformation: Overview
Drug Biotransformation: Overview
