Related Experiment Video
Updated: Jun 16, 2026

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
Published on: May 14, 2020
[Preclinical evaluation of coated knee implants for allergic patients]
J Reich1, L Hovy, H-L Lindenmaier
1Forschung & Entwicklung, Aesculap AG, Am Aesculap-Platz, 78532, Tuttlingen, Deutschland. jan.reich@aesculap.de
Background:
10-15% of the population show allergic reactions against skin contact to metals as nickel, cobalt or chromium and have thus a risk of not tolerating implants containing those materials. The relationship between periimplantary hypersensivity reaction and given cutaneous contact allergy is currently unknown. A new developed multilayer coating system is supposed to prevent long-term allergic reactions that may result from uncoated implants.
Methods:
Stability and function (concerning bonding durability, wear and ion release to the serum) of the multilayer coating system has been examined in a test series.
Results:
The specific architecture of the multilayer coating system evidences a very good bonding durability. The results of the test in the simulator show a reduction of wear of approximately 60% compared to the uncoated implants. Ion concentrations within the serum of the wear tests were by magnitudes lower than those measured in reference tests on uncoated components.
Conclusion:
The results of the preclinical evaluation prove that the durability and function of the multilayer coating system are as intended.
