Related Experiment Video
Updated: Jun 16, 2026

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
Published on: June 11, 2011
Pathology in children of HIV women
Ana Pilar Nso Roca1, C García-Bermejo García-Bermejo, B Larru
1Servicio Inmuno-Pediatría, Hospital Universitario La Paz, Madrid, Spain. ananso@yahoo.es
Objective:
To assess the frequency of perinatal pathology in children exposed to antiretrovirals in perinatal period.
Design:
Retrospective observational cohort study.
Methods:
Retrospective observational cohort study. Data collected among uninfected children born to HIV-infected women followed up from 1994 to 2006 in a tertiary Hospital. 220 uninfected children were studied. Factors studied included maternal, obstetrical and pediatric variables.
Results:
The most common disorder found among children exposed to antiretroviral drugs was anemia (84%); 6,4% of children had neutropenia and more than 24% had thrombocytosis, a finding never described before. Prematurity (24%) and low birth weight (23.6%) rates were high. Several congenital malformations were found: Poland syndrome, angiomas, hypospadias, Pierre-Robin sequence, trisomy 8, craniostosis and others. Long-term follow-up revealed neurological, cardiological and ophthalmological pathologies.
Conclusion:
Some pathologies are frequent among children exposed to antiretroviral agents during perinatal life. It is crucial to carry out long-term studies to assess the safety of this therapy.
Related Concept Videos
Sexually Transmitted Infections
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Cryptococcal Meningitis
Cytomegalovirus Disease
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pharmacokinetics in Pediatric Patients: Drug Excretion
