Potential for functional redundancy in EGF and TGFalpha signaling in desmoid cells: a cDNA microarray analysis

Sylvia H Trang1, David E Joyner, Timothy A Damron

  • 1SARC Laboratory, Sarcoma Services, Department of Orthopaedics and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.

Summary

Epidermal Growth Factor (EGF) and Transforming Growth Factor alpha (TGFα) show significant functional redundancy in desmoid tumor cells. This suggests a shared evolutionary origin, impacting gene expression patterns over time.

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