Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells

Pietro Luigi Poliani1, Kai Kisand, Veronica Marrella

  • 1Department of Pathology, University of Brescia, P.le Spedali Civili 1, 25123, Brescia, Italy.

Summary

Autoimmune regulator (AIRE) expressing cells in human peripheral tissues, like lymph nodes, may prevent autoimmunity. These cells, identified as activated dendritic cells, express tissue-restricted antigens and tolerogenic molecules.

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