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Updated: Jun 16, 2026
Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
Published on: October 20, 2019
Spontaneous liver rupture associated with hydatidiform mole pregnancy
Jason M Vanatta1, Humberto Monge, Clark A Bonham
1From the Methodist Transplant Institute/University of Tennessee, Division of Transplantation, Memphis, Tennessee; and Stanford University, Division of Transplantation, Palo Alto, California.
Background:
Spontaneous liver rupture is a rare occurrence during pregnancy.
Case:
A young woman presented early in her pregnancy with severe abdominal pain, tachycardia, and hypotension. She was taken emergently to the operating room with a presumed diagnosis of ruptured ectopic pregnancy. Exploration revealed that her hemoperitoneum resulted from large fractures within her liver. During her resuscitation and treatment, a transvaginal ultrasound scan revealed a hydatidiform molar pregnancy. On resolution of postoperative complications and complete recovery, the patient was discharged home.
Conclusion:
This case illustrates that, although very unusual, hydatidiform molar pregnancies should be considered as a precipitating factor for spontaneous liver rupture.
