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Updated: Jun 16, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Stroke in a patient with a surgically ligated left atrial appendage: should warfarin be continued after left atrial
Khalil Kanjwal1, William R Colyer
1Division of Cardiology, Section of Interventional Cardiology, University of Toledo Medical Center, 3000 Arlington Avenue, Toledo, OH 43614, USA.
Insights
An incompletely ligated left atrial appendage caused embolic stroke in a patient. Prompt anticoagulation after surgery could have prevented this serious complication.
Area of Science:
- Cardiology
- Neurology
- Vascular Surgery
Background:
- The left atrial appendage is a common source of thromboembolism, particularly in patients with atrial fibrillation.
- Surgical ligation of the left atrial appendage is performed to reduce stroke risk during cardiac procedures.
Observation:
- A 74-year-old woman experienced embolic stroke affecting the brainstem and cerebellum.
- Past medical history included coronary bypass surgery with prophylactic left atrial appendage ligation.
Findings:
- Investigations revealed the source of emboli was an incompletely ligated left atrial appendage.
- This anatomical anomaly led to recurrent clot formation and subsequent embolism.
Implications:
- Incomplete left atrial appendage ligation poses a significant risk for embolic events.
- Post-operative anticoagulation management is crucial to mitigate embolism risk after cardiac surgery.
- This case highlights the importance of complete surgical technique and vigilant anticoagulation strategies.
Abstract:
We report on a 74-year-old woman who presented with embolic stroke of the brainstem and right cerebellum. She had undergone coronary bypass surgery and prophylactic ligation of the left atrial appendage in the past. On further investigations, a source of emboli was found to be an incompletely ligated left atrial appendage. Anticoagulation with warfarin if started after surgery would have reduced the risk of embolism in this patient.
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