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Retinal hemorrhages and apparent life-threatening events
Ana Isabel Curcoy1, Victoria Trenchs, Marta Morales
1Department of Pediatrics, Hospital Universitari Sant Joan de Déu, Barcelona, Spain. acurcoy@hsjdbcn.org
Insights
Retinal hemorrhages are rare in apparent life-threatening events (ALTEs) in children under two. If found, it suggests nonaccidental head trauma requires investigation.
Area of Science:
- Pediatrics
- Ophthalmology
- Forensic Medicine
Background:
- Apparent life-threatening events (ALTEs) in infants and young children can mimic nonaccidental head trauma.
- Retinal hemorrhages are a key indicator in diagnosing abusive head trauma.
- The association between ALTEs and retinal hemorrhages requires clarification for accurate diagnosis.
Purpose of the Study:
- To determine the prevalence of retinal hemorrhages in children diagnosed with ALTEs.
- To aid in the differential diagnosis between ALTEs and nonaccidental head trauma.
- To establish the likelihood of retinal hemorrhages solely due to ALTEs.
Main Methods:
- Prospective study of 108 children aged 15 days to 2 years with ALTEs.
- Ophthalmologic examinations conducted within 72 hours of admission.
- Further investigations for systemic disorders or maltreatment if hemorrhages were detected.
Main Results:
- No retinal hemorrhages were observed in any of the 108 children with ALTEs.
- No cases of child abuse were identified in the study cohort.
- The upper limit of 95% confidence for retinal hemorrhages resulting from ALTEs alone is 0.028.
Conclusions:
- ALTEs alone are an unlikely cause of retinal hemorrhages in children under 2 years.
- The presence of retinal hemorrhages in this age group warrants investigation for nonaccidental injury.
- Distinguishing ALTEs from abusive head trauma is critical for appropriate medical and legal management.
Objective:
To determine the prevalence of retinal hemorrhages in apparent life-threatening events (ALTEs) with the purpose of facilitating the differential diagnosis of the cases of nonaccidental head trauma.
Methods:
Prospective study on children aged 15 days to 2 years admitted to our hospital with a diagnosis of an ALTE over a period of 2 years (May 2004-May 2006). All the children underwent detailed ophthalmologic examination within 72 hours of admission. If retinal hemorrhages were detected, further investigation was undertaken to rule out systemic disorder or maltreatment.
Results:
One hundred eight children with an ALTE were examined. No patient was found to have retinal hemorrhages nor was any found to have experienced child abuse. Therefore, using the Hanley rule of 3, we can be confident to an upper limit of 95% that the chance of retinal hemorrhages occurring as a result of an ALTE alone is at the most 0.028.
Conclusions:
Apparent life-threatening events alone are unlikely to cause retinal hemorrhages in children younger than 2 years. Therefore, if retinal hemorrhages are detected, investigation into the possibility of nonaccidental injury is essential.
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