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Published on: June 11, 2020
[Generalized epileptic seizures in an infant due to passive exposure to cocaine]
S Aguilera1, C Salado, I Díaz López
1Servicio de Pediatría, Hospital Virgen del Camino, Pamplona, Spain.
Insights
Passive smoke exposure to cocaine can cause seizures in infants. Urine toxicology screening is recommended for infants experiencing unexplained seizures.
Area of Science:
- Pediatric Neurology
- Toxicology
Background:
- The differential diagnosis for afebrile seizures in infants is broad.
- Identifying the cause of seizures is critical for appropriate management.
Observation:
- A 7-month-old infant experienced two generalized tonic-clonic seizures within 23 hours.
- Initial evaluations including laboratory tests, cerebral echography, and EEG were normal.
- Urine toxicology initially tested positive for cocaine, with subsequent negative results.
Findings:
- The infant's seizures were linked to passive exposure to cocaine smoke.
- The child had no further seizures and exhibited normal development during a six-month follow-up.
Implications:
- Passive cocaine inhalation is a potential cause of seizures in infants.
- Routine urine toxicology screening is advised for infants with unexplained afebrile seizures.
- Increased awareness of risks associated with passive cocaine exposure is necessary due to rising crack use.
Background:
The differential diagnosis of afebrile seizures in the first year of life is extensive.
Case Report:
A 7-month old infant presented two afebrile generalized tonic-clonic seizures in 23 hours; her psychomotor and growth development followed a normal course. Laboratory analysis, cerebral echography and electroencephalogram were normal. Urine toxicology was positive for cocaine on two occasions. A negative urine sample was obtained 48 hours later. The parents denied drug abuse but explained a recent exposure to smoke some hours before the episode. The patient had no seizures in the following six months, with normal psychomotor development.
Discussion:
Passive inhalation of cocaine is associated with seizures in infants. There is no perception of the risk of passive exposure to cocaine in our country, despite the increasing consumption of crack in young adults. Urine toxicology should be systematically included in the study of a first afebrile seizure in an infant.
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