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Related Concept Videos

Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Contact-dependent Signaling01:19

Contact-dependent Signaling

Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
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Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...

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Related Experiment Video

Updated: Jun 16, 2026

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface
11:00

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Published on: October 2, 2016

Controlled single atom and single molecule contacts.

R Berndt1, J Kröger, N Néel

  • 1Institut für Experimentelle und Angewandte Physik, Christian-Albrechts-Universität zu Kiel, D-24098 Kiel, Germany.

Physical Chemistry Chemical Physics : PCCP
|January 23, 2010
PubMed
Summary
This summary is machine-generated.

Scanning tunnelling microscopy (STM) allows precise atomic and molecular contact preparation for electron transport studies. Recent research explores quantum transport through magnetic atoms and C(60) molecules using STM.

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Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

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Last Updated: Jun 16, 2026

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface
11:00

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Published on: October 2, 2016

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy
09:48

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

Published on: February 27, 2015

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy
10:37

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Published on: March 16, 2020

Area of Science:

  • Surface science
  • Quantum electronics
  • Nanotechnology

Background:

  • Scanning tunnelling microscopy (STM) enables atomic-scale manipulation and characterization.
  • Investigating electron transport through single-molecule junctions is crucial for molecular electronics.
  • Understanding quantum transport phenomena is key to developing novel electronic devices.

Purpose of the Study:

  • To present recent investigations on quantum transport through single magnetic atoms and C(60) molecules.
  • To highlight the capabilities of STM in preparing and characterizing such contacts.
  • To explore the interplay between geometry, electronic properties, and quantum transport.

Main Methods:

  • Utilizing scanning tunnelling microscopy (STM) for contact preparation.
  • Employing spectroscopic modes for detailed characterization of atomic/molecular contacts.
  • Investigating electron transport properties through single-atom and single-molecule junctions.

Main Results:

  • Demonstrated STM's ability to form stable contacts with individual magnetic atoms and C(60) molecules.
  • Characterized the geometric and electronic properties of these contacts using STM imaging and spectroscopy.
  • Presented findings on quantum transport phenomena occurring through these nanoscale junctions.

Conclusions:

  • STM is a powerful tool for creating and studying single-atom and single-molecule electronic devices.
  • Quantum transport through magnetic atoms and C(60) molecules exhibits unique characteristics.
  • This research paves the way for future advancements in molecular electronics and spintronics.