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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Devascularization of head and neck paragangliomas by direct percutaneous embolization
Umut Ozyer1, Ali Harman, Erkan Yildirim
1Department of Radiology, Baskent Universitesi Tip Fakultesi Hastanesi, Fevzi Cakmak Cd. 10., Sk. No. 45, 06490, Bahcelievler/Ankara, Turkey. umut_ozyer@yahoo.com
Cardiovascular and Interventional Radiology
|January 23, 2010
Summary
Direct intratumoral injection of n-butyl cyanoacrylate (NBCA) or Onyx offers a safe and effective method for preoperative embolization of head and neck paragangliomas, improving tumor devascularization.
Area of Science:
- Interventional Radiology
- Vascular Surgery
- Oncology
Background:
- Transarterial embolization is used for head and neck paragangliomas to reduce blood loss.
- This method is often incomplete due to complex tumor vascularity and arteriovenous shunts.
Purpose of the Study:
- To evaluate the safety and efficacy of direct percutaneous intratumoral injection of NBCA or Onyx for preoperative embolization of head and neck paragangliomas.
Main Methods:
- Retrospective analysis of 10 patients (32-82 years) with head and neck paragangliomas.
- Direct intratumoral injections performed under ultrasound and fluoroscopic guidance.
- Embolization agents used: n-butyl cyanoacrylate (NBCA) and Onyx.
Main Results:
- Complete or near-complete devascularization achieved in all tumors.
- Successful treatment in cases with multiple small-caliber feeders and incomplete transarterial embolization.
- No technical or clinical complications reported.
Conclusions:
- Percutaneous direct injection of NBCA or Onyx is a feasible, safe, and effective preoperative embolization technique for head and neck paragangliomas.
- This approach is particularly beneficial for complex vascular structures and incomplete devascularization.
