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Updated: Jun 16, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Compliance with group B streptococcus testing prior to labor and delivery
Elizabeth Rodriguez1, Christina A Raker, Michael J Paglia
1The Alpert Medical School of Brown University, Providence, Rhode Island 02905, USA.
Most full-term pregnancies receive group B streptococcus (GBS) screening, but timely adherence to CDC guidelines for GBS testing is suboptimal. Rapid GBS testing is not essential for this patient group.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Public Health
Background:
- Group B Streptococcus (GBS) screening is crucial for preventing neonatal infections.
- The Centers for Disease Control and Prevention (CDC) provide specific guidelines for GBS screening timing.
- Evaluating screening practices ensures adherence to established public health recommendations.
Purpose of the Study:
- To assess the adherence to CDC-recommended GBS screening protocols in full-term pregnancies.
- To determine the necessity of rapid GBS testing for women in full-term gestation.
Main Methods:
- Retrospective cohort analysis at a large academic institution.
- Inclusion criteria: full-term infants (>37 weeks) with documented prenatal care.
- Primary outcome: documented GBS screening rates and timing.
Main Results:
- 95.76% of women underwent GBS screening prior to labor and delivery, exceeding the 90% hypothesis.
- Only 80.61% of women had GBS cultures performed within the CDC-recommended 35-37 week gestational window.
- This timely screening rate was significantly lower than the 90% hypothesis (P < 0.001).
Conclusions:
- While overall GBS screening is high, adherence to recommended gestational timing is insufficient.
- Current screening practices suggest rapid GBS testing is not a necessary intervention for full-term pregnancies.
- Optimizing screening timing remains critical for effective GBS prevention strategies.
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