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Updated: Jun 16, 2026
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Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
[Hemodynamics analysis of a stented aortic bifurcation]
1Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China.
Summary
Double stent implantation in aortic arch dissections can lead to poor blood flow and low shear stress when struts protrude into the left subclavian artery (LSA). This may cause complications, suggesting bifurcated stents are preferable for bifurcation lesions.
Area of Science:
- Biomedical Engineering
- Cardiovascular Research
- Medical Device Design
Context:
- Aortic arch dissections involving the left subclavian artery (LSA) often require complex stent implantation.
- Current double stent techniques may lead to suboptimal hemodynamics in branch origins.
Purpose:
- To investigate the hemodynamic impact of double stent implantation in the aortic arch and LSA using computational fluid dynamics (CFD).
- To analyze blood flow speed and wall shear stress changes caused by protruding stent struts.
Summary:
- Simulations revealed that stent struts protruding into the LSA inlet significantly decrease blood speed and create low shear stress zones.
- These hemodynamic changes are associated with increased risk of thrombogenesis, neointimal hyperplasia, and in-stent restenosis.
Impact:
- Findings suggest that protruding stent struts in bifurcation lesions can have detrimental hemodynamic consequences.
- Recommends the use of dedicated bifurcated stents to optimize treatment outcomes for aortic arch branch lesions.
