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[Lentinan induces the expression of human-beta-defensin-2 in pulmonary epithelial cells]
Yan Zhou1, Birong Dong, Lihua Teng
1Department of Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.
Abstract:
To determine whether lentinan could upregulate the expression of human-beta-defensin-2(HBD-2) in pulmonary epithelial cells (SPC-A-1), we stimulated pulmonary epithelial cells with lentinan and detected the expression of HBD-2mRNA by RT-PCR test. The results demonstrated that the expression of HBD-2mRNA in SPC-A-1 could be induced by lentinan in a concentration and time-dependent manner.
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