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The Retinoblastoma Gene

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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Related Experiment Video

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Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

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Congenital mesoblastic nephroma

Aaron M Gruver¹, Donna E Hansel, Daniel J Luthringer

¹Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA.

The Journal of Urology

|January 26, 2010

Summary

No abstract available in PubMed .

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