Related Experiment Video
Updated: Jun 16, 2026

Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking
Published on: August 6, 2013
Early emerging nicotine-dependence symptoms: a signal of propensity for chronic smoking behavior in adolescents
Lisa Dierker1, Robin Mermelstein
1Psychology Department, Wesleyan University, Middletown, CT 06459, USA. ldierker@wesleyan.edu
Objective:
To evaluate the predictive validity of nicotine-dependence symptoms in 9th- and 10th-grade adolescents.
Study Design:
A total of 594 adolescents who had not smoked more than 100 cigarettes in their lifetime and 152 adolescents who had smoked more than 100 cigarettes in their lifetime were included in the analysis. The predictive validity of 10 nicotine-dependence items administered at baseline was evaluated at the 24-month follow-up assessment.
Results:
For those who smoked fewer than 100 cigarettes, higher levels of experienced nicotine-dependence symptoms at baseline, as well as individual symptoms, predicted current and daily smoking behavior at the 24-month follow-up, over and above baseline smoking. For adolescents who had smoked more than 100 cigarettes at baseline, the level of nicotine dependence and individual symptom endorsement did not predict smoking behavior at the 24-month follow-up.
Conclusions:
Our findings demonstrate that early emerging dependence symptoms reported at low levels of smoking exposure signal a greater propensity for continued smoking behavior not accounted for by current or past smoking exposure. Screening for these early emerging symptoms among novice adolescent smokers represents an important and unused tool in tobacco control efforts aimed at preventing the development of chronic smoking patterns.
Related Concept Videos
Drug Dependence
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
CNS Depressants: Alcohol and Nicotine
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
