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Bone: adiposity and bone accrual-still an established paradigm?
Masanobu Kawai1, Clifford J Rosen
1Skeletal Research Laboratory, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074-7205, USA.
Nature Reviews. Endocrinology
|January 26, 2010
Summary
Obesity may not protect against bone fractures as previously thought. Emerging research suggests a potential link between excess weight and increased skeletal fragility, challenging long-held clinical beliefs.
Area of Science:
- Orthopedics
- Endocrinology
- Gerontology
Background:
- Clinical practice has long assumed obesity protects against skeletal failure.
- This long-standing paradigm has influenced treatment and prevention strategies for bone health.
Purpose of the Study:
- To investigate the relationship between obesity and skeletal fragility.
- To challenge the established clinical tenet that obesity is protective against bone issues.
Main Methods:
- The study involved analyzing data related to body mass index and bone health outcomes.
- Specific methodologies likely included bone density scans and fracture incidence rates.
Main Results:
- Findings indicate that obesity may not confer skeletal protection.
- The study suggests a potential for increased skeletal fragility in individuals with obesity.
Conclusions:
- The traditional view of obesity as protective against skeletal failure requires re-evaluation.
- Further research is needed to fully understand the complex interplay between obesity and bone health.
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