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Related Experiment Video

Updated: Jun 16, 2026

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
06:29

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Published on: October 20, 2023

[Damage control surgery for acute mesenteric ischemia].

Jian-Feng Gong1, Wei-Ming Zhu, Xing-Jiang Wu

  • 1Department of General Surgery, Jinling Hospital, Nanjing 200000, China.

Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery
|January 26, 2010
PubMed
Summary
This summary is machine-generated.

Damage control surgery (DCS) significantly improves survival rates for acute mesenteric ischemia (AMI) patients. Early thrombectomy and thrombolysis are crucial for managing AMI and preventing thrombosis progression.

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Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Vascular Surgery

Context:

  • Acute mesenteric ischemia (AMI) presents a critical surgical challenge with high mortality.
  • Damage control surgery (DCS) offers a staged approach for managing complex abdominal catastrophes.
  • This study evaluates DCS in a cohort of patients with acute mesenteric ischemia.

Purpose:

  • To assess the efficacy and outcomes of damage control surgery (DCS) in patients diagnosed with acute mesenteric ischemia (AMI).
  • To analyze the impact of thrombectomy and thrombolysis within the DCS framework for AMI.
  • To determine survival rates and identify factors influencing outcomes in AMI patients undergoing DCS.

Summary:

  • A retrospective analysis of 15 acute mesenteric ischemia (AMI) patients treated with damage control surgery (DCS) was conducted.
  • The staged DCS approach involved bowel resection, thrombectomy, ICU resuscitation, and thrombolysis before definitive reconstruction.
  • Survival rate was 66.7% (10 out of 15), with no parenteral nutrition dependence among survivors. Key interventions included thrombectomy and thrombolysis.

Impact:

  • Damage control surgery (DCS) demonstrates a positive impact on survival for acute mesenteric ischemia (AMI) patients.
  • The findings underscore the importance of thrombectomy and thrombolysis in preventing disease progression.
  • This approach offers a viable strategy for managing severe AMI, potentially improving patient outcomes.