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Related Experiment Video

Updated: Jun 16, 2026

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

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Published on: August 27, 2013

Acoustic programming in step-split-flow lateral-transport thin fractionation.

Claire Ratier¹, Mauricio Hoyos

¹Laboratoire de Physique et Mécanique des Milieux Hétérogenes, UMR7636 CNRS, ESPCI, 10, Rue Vauquelin, 75231 Paris Cedex 05, France.

Analytical Chemistry

|January 27, 2010

Summary

This summary is machine-generated.

We developed a new hydrodynamic acoustic sorter (HAS) that uses acoustic forces and gravity for efficient particle separation. This method achieves high-purity separation of microparticles, significantly reducing processing time.

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A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice

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Published on: November 23, 2015

Area of Science:

Fluid dynamics
Acoustofluidics
Particle separation technology

Background:

Traditional particle separation methods face limitations in efficiency and speed.
Micrometer-sized particle separation is crucial in various scientific and industrial applications.

Purpose of the Study:

To introduce a novel hydrodynamic acoustic sorter (HAS) for efficient separation of micrometer-sized particles.
To investigate the combined effect of acoustic forces and gravity in split-flow lateral-transport thin (SPLITT)-like fractionation channels.

Main Methods:

Utilizing ultrasonic standing waves to generate acoustic forces within the channel thickness.
Employing split-flow lateral-transport thin (SPLITT)-like fractionation channels.
Conducting preliminary experiments with latex particles (5 and 10 micrometers) and performing numerical simulations.

Main Results:

Achieved total binary separation of 5 and 10 micrometer diameter latex particles.
Numerical simulations showed excellent agreement with experimental results.
Demonstrated a separation time improvement of approximately one order of magnitude compared to conventional SPLITT fractionation.

Conclusions:

The proposed hydrodynamic acoustic sorter (HAS) offers a significant advancement in particle separation technology.
The technique shows potential for extension to complex biological samples like biomimetic particles and blood cells.
Further optimization could lead to even greater improvements in separation efficiency and speed.