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Carcinoma of the vulva with sarcomatoid features: a case report with immunohistochemical study
G Santeusanio1, S Schiaroli, L Anemona
1Cattedra di Anatomia e Istologia Patologica, II Università di Roma, Tor Vergata, Italy.
Gynecologic Oncology
|February 1, 1991
Abstract:
A tumor of the vulva with sarcomatoid features was studied by immunocytochemistry to characterize the phenotype of the spindle-shaped and giant cells. Sarcomatoid-looking cells were positive for intermediate filament keratin polypeptides of stratified epithelium. These results favor histogenesis of the sarcomatoid-looking cells from a metaplastic alteration of the malignant squamous component.