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Normolipemic tuberous xanthomas.

Ajay Pal Singh1, Shilpi Sikarwar, O P Jatav

  • 1Department of Medicine, G.R. Medical College, Gwalior - 474 009, MP, India. drajaypalsingh4@rediffmail.com

Indian Journal of Dermatology
|January 27, 2010
PubMed
Summary
This summary is machine-generated.

This study reports a rare case of normolipemic tuberous xanthomas in a 50-year-old male. Despite widespread lesions, his lipid levels and routine tests were normal, highlighting an unusual presentation.

Keywords:
Cutaneousnormolipemictuberous xanthoma

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Area of Science:

  • Dermatology
  • Lipidology
  • Pathology

Background:

  • Xanthomas are cutaneous manifestations frequently linked to dyslipidemia.
  • Tuberous xanthomas are typically associated with significantly elevated lipid levels.
  • Normolipemic xanthomas represent a rare clinical entity.

Purpose of the Study:

  • To present a unique case of tuberous xanthomas occurring in a patient with normal lipid profiles.
  • To discuss the diagnostic challenges and implications of normolipemic xanthomas.

Main Methods:

  • Case presentation of a 50-year-old male with multiple tuberous xanthomas.
  • Inclusion of routine investigations, systemic examination, and lipid profile.
  • Histopathological examination of a nodular lesion.

Main Results:

  • The patient presented with widespread tuberous xanthoma lesions.
  • All routine investigations, systemic examinations, and lipid profiles were within normal limits.
  • Histopathology confirmed the presence of foamy macrophages in the dermis, characteristic of xanthomas.

Conclusions:

  • This case illustrates an uncommon presentation of tuberous xanthomas in the absence of hyperlipidemia.
  • Normolipemic xanthomas warrant careful consideration in the differential diagnosis of skin lesions, even with normal lipid panels.
  • Further research may be needed to elucidate the specific mechanisms behind normolipemic xanthoma formation.