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Related Concept Videos

Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers01:26

Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers

Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

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Subcutaneous Autologous Serum Therapy in Chronic Spontaneous Urticaria.

Indian journal of dermatology·2017
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Updated: Jun 16, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Chronic urticaria and treatment options.

Kiran Vasant Godse1

  • 1Shree Skin Centre, 22, L Market, Sector 8, Nerul, Navi Mumbai - 400 706, India. drgodse@yahoo.co.in

Indian Journal of Dermatology
|January 27, 2010
PubMed
Summary

Chronic urticaria presents diversely, often with unknown causes. Treatment involves avoiding triggers, counseling, and medications like antihistamines and immunosuppressives.

Area of Science:

  • Dermatology
  • Immunology

Background:

  • Chronic urticaria (CU) exhibits varied clinical presentations and etiologies.
  • Idiopathic cases are prevalent, posing diagnostic challenges.

Purpose of the Study:

  • To outline the diverse clinical spectrum and causes of chronic urticaria.
  • To review current and emerging treatment strategies for chronic urticaria.

Main Methods:

  • Literature review of chronic urticaria presentations and treatments.
  • Synthesis of information on primary prevention, pharmacotherapy, and immunosuppressive agents.

Main Results:

  • CU has a wide range of clinical manifestations.
  • Effective management requires identifying and avoiding triggers.
Keywords:
Urticariaautoantibodiesautoimmune urticaria

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  • Pharmacological options include antihistamines, leukotriene receptor antagonists, corticosteroids, and various immunosuppressants.
  • Conclusions:

    • Despite extensive investigation, the cause of chronic urticaria remains elusive in many patients.
    • A multimodal treatment approach, including trigger avoidance and targeted pharmacotherapy, is essential for managing chronic urticaria.