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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: Jun 16, 2026

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
08:55

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence

Published on: November 2, 2014

Recurrent ovarian malignancy presenting as cutaneous metastasis.

Shilpaja J Karpate1, Swarnlata L Samal, Suchi M Jain

  • 1Department of Obstetrics and Gynecology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra, India. sjk_12@yahoo.co.in

Indian Journal of Dermatology
|January 27, 2010
PubMed
Summary

Cutaneous metastasis, a rare ovarian carcinoma complication, presented as clitoral and skin nodules. Despite a poor prognosis, the patient showed a positive response and survived longer than anticipated.

Keywords:
Skin metastasisovarian carcinomaprognosis

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Last Updated: Jun 16, 2026

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
08:55

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence

Published on: November 2, 2014

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
05:42

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum

Published on: January 26, 2024

Area of Science:

  • Oncology
  • Dermatology
  • Gynecologic Oncology

Background:

  • Cutaneous metastasis from ovarian carcinoma is an infrequent clinical occurrence.
  • Ovarian cancer commonly metastasizes to the peritoneum, liver, lungs, and lymph nodes, but skin involvement is rare.

Purpose of the Study:

  • To report a rare case of cutaneous metastasis from ovarian carcinoma.
  • To highlight the diagnostic approach and clinical course of this uncommon presentation.

Main Methods:

  • Case report of a patient presenting with clitoral and skin nodules.
  • Histopathological examination of the nodules to confirm metastatic ovarian carcinoma.

Main Results:

  • Histopathology confirmed cutaneous metastasis of ovarian carcinoma.
  • The patient, despite a generally poor prognosis associated with such metastasis, demonstrated a favorable response to treatment.
  • The patient survived significantly longer than the typically expected four months for this condition.

Conclusions:

  • Cutaneous metastasis from ovarian carcinoma, though rare, can occur and present as nodules.
  • This case underscores the importance of considering unusual metastatic sites in ovarian cancer patients.
  • Aggressive management may lead to improved survival outcomes even in cases with advanced or rare metastatic patterns.