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The use of quantum dot nanocrystals in multicolor flow cytometry

Pratip K Chattopadhyay1, Stephen P Perfetto, Joanne Yu

  • 1ImmunoTechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA. pchattop@mail.nih.gov

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
|January 27, 2010
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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...