Cataracts and uveitis
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Updated: Jun 16, 2026

Modeling Cataract Surgery in Mice
Published on: December 1, 2023
Maria Jancevski1, C Stephen Foster
1Massachusetts Eye Research and Surgery Institution, Cambridge, Massachusetts 02142, USA.
Abstract:
Most uveitics enjoy good vision despite potentially sight-threatening complications including cataract development. In those patients who develop cataracts, successful surgery stems from educated patient selection, careful surgical technique, and aggressive preoperative and postoperative control of inflammation. While commonly accepted in the adult patient population, recent investigations reflect the increased tolerance for primary intraocular lens placement in the pediatric cohort. The role of absolute control of inflammation continues with greater focus on immunomodulatory therapies. However, these agents bear their own side effect and complication profiles. Cataract extraction with intraocular lens implantation in the setting of meticulous control of inflammation can optimize visual outcome in adults and children with uveitis.
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