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Related Experiment Video

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Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Published on: August 1, 2025

Concurrent intracranial and thoracic aortic aneurysms.

Gregory A Kuzmik¹, Marina Feldman, Maryann Tranquilli

¹Yale University School of Medicine, New Haven, Connecticut, USA.

The American Journal of Cardiology

|January 28, 2010

Summary

Patients with thoracic aortic aneurysm (TAA) have a significantly higher prevalence of intracranial aneurysms (ICA), suggesting routine screening for ICA in TAA patients is warranted. This finding is crucial for managing these vascular conditions.

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Area of Science:

Vascular Surgery
Neurology
Radiology

Background:

Thoracic aortic aneurysm (TAA) and intracranial aneurysm (ICA) share underlying pathological mechanisms.
The prevalence of concurrent ICA in TAA patients remains largely unknown.
Understanding this association is vital for patient management and screening protocols.

Purpose of the Study:

To determine the prevalence of intracranial aneurysms (ICA) in patients diagnosed with thoracic aortic aneurysm (TAA).
To assess if TAA patients warrant screening for concurrent ICA.
To identify factors influencing the co-occurrence of TAA and ICA.

Main Methods:

Retrospective analysis of 212 TAA patients with available brain imaging (CTA or MRA).
Bivariate statistical analysis, including Fisher's exact test, was employed.
Comparison of ICA prevalence based on TAA location, hypertension, smoking history, race, age, and gender.

Main Results:

A 9.0% prevalence of concurrent ICA was observed in TAA patients, nine times higher than the general population.
Descending TAA location (33%) showed a significantly higher ICA prevalence compared to ascending TAA (7.1%).
Hypertension (11.8%) and smoking history were associated with increased ICA prevalence in TAA patients.

Conclusions:

Patients with thoracic aortic aneurysm (TAA) face an elevated risk of developing intracranial aneurysms (ICA).
Screening for ICA in patients with TAA is recommended due to the increased prevalence.
TAA location and comorbidities like hypertension significantly impact concurrent ICA risk.