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Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

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Updated: Jun 16, 2026

Venous Thrombosis Assay in a Mouse Model of Cancer

Venous Thrombosis Assay in a Mouse Model of Cancer

Published on: January 5, 2024

Statins decrease the occurrence of venous thromboembolism in patients with cancer.

Danai Khemasuwan¹, Matthew L Divietro, Kawin Tangdhanakanond

¹Albert Einstein Medical Center, Philadelphia, PA19141, USA. danai_md@hotmail.com

The American Journal of Medicine

|January 28, 2010

Summary

This summary is machine-generated.

Statin use significantly reduced venous thromboembolism in solid organ tumor patients. This finding suggests a potential pleiotropic benefit of statins beyond cholesterol reduction, warranting further investigation.

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Last Updated: Jun 16, 2026

Venous Thrombosis Assay in a Mouse Model of Cancer

Venous Thrombosis Assay in a Mouse Model of Cancer

Published on: January 5, 2024

Area of Science:

Oncology
Cardiology
Pharmacology

Background:

Growing evidence suggests statins may reduce venous thromboembolism (VTE) in certain patient populations.
This study investigates the association between statin use and VTE occurrence in patients diagnosed with solid organ tumors.

Purpose of the Study:

To determine the impact of statin therapy on the incidence of venous thromboembolism in patients with solid organ malignancy.

Main Methods:

A retrospective case-control study analyzed 740 patients with solid organ tumors admitted between 2004-2007.
Patients on anticoagulation prior to admission were excluded; statin use was categorized based on duration.
VTE occurrence and risk factors were recorded for analysis.

Main Results:

The overall VTE incidence was 18%.
Patients receiving statins had a significantly lower VTE rate (8%) compared to the control group (21%), with an odds ratio of 0.33.
Logistic regression confirmed statin use as an independent protective factor against VTE, even after adjusting for known risk factors.

Conclusions:

Statin use is associated with a significant reduction in venous thromboembolism occurrence among solid organ tumor patients.
The findings highlight a potential pleiotropic effect of statins that merits further research.
This suggests statins could play a role in VTE prophylaxis in this vulnerable patient group.