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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
09:12

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Published on: March 27, 2018

Effect of body mass index on early and late mortality after coronary artery bypass grafting

Albert H M van Straten1, Sander Bramer, Mohamed A Soliman Hamad

  • 1Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands.

The Annals of Thoracic Surgery
|January 28, 2010
PubMed

Insights

Underweight patients face higher early mortality after coronary artery bypass graft (CABG) surgery. Morbid obesity independently predicts increased late mortality in CABG patients, highlighting BMI's impact on surgical outcomes.

Area of Science:

  • Cardiovascular Surgery
  • Obesity Medicine
  • Clinical Outcomes Research

Background:

  • The impact of obesity on outcomes following coronary artery bypass graft (CABG) surgery is debated.
  • This study investigates body mass index (BMI) and comorbidities' predictive value for mortality after CABG.

Purpose of the Study:

  • To determine the predictive value of preoperative body mass index (BMI) on early and late mortality in patients undergoing isolated CABG.
  • To analyze the combined effect of BMI and comorbidities on surgical outcomes.

Main Methods:

  • A retrospective analysis of 10,268 patients undergoing isolated CABG between January 1998 and December 2007.
  • Patients were stratified into five BMI categories: underweight, normal weight, overweight, obese, and morbidly obese.
  • Multivariate logistic and Cox regression models were used to assess mortality predictors.

Main Results:

  • Underweight was significantly associated with increased early mortality (HR 2.63, p=0.025).
  • Morbid obesity emerged as an independent predictor of late mortality (HR 1.67, p=0.007).

Conclusions:

  • Underweight status is an independent predictor of early mortality in isolated CABG patients.
  • Morbid obesity is an independent predictor of late mortality following isolated CABG.
Abstract

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