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Updated: Jun 16, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Third-time aortic valve replacement: patient characteristics and operative outcome
Kasra Shaikhrezai1, Giordano Tasca, Mohamed Amrani
1Department of Cardiac Surgery, Harefield Hospital, Royal Brompton and Harefield NHS Trust, London, United Kingdom.
Third-time aortic valve replacement (AVR) is a rare but feasible procedure with low operative mortality and good long-term survival. This surgery also leads to significant reduction in left ventricular mass.
Area of Science:
- Cardiac Surgery
- Cardiovascular Research
- Thoracic Surgery
Background:
- Reoperative cardiac surgery, including third-time aortic valve replacement (AVR), is increasingly common.
- Third-time AVR is a rare but significant procedure in managing complex cardiac cases.
Purpose of the Study:
- To retrospectively analyze the outcomes of third-time aortic valve replacement (AVR).
- To evaluate preoperative characteristics, prosthetic valve pathology, and postoperative results of third-time AVR.
Main Methods:
- Retrospective analysis of 49 patients undergoing third-time AVR between 1990 and 2005.
- Data collected included patient demographics, prosthesis types, pathology, morbidity, mortality, and echocardiographic findings.
Main Results:
- In-hospital mortality was 4.1%.
- Five-year freedom from reoperation was 84%, and long-term survival was 79%.
- Factors associated with decreased survival included age, female sex, and elevated postoperative left ventricular mass, which significantly regressed post-surgery.
Conclusions:
- Third-time AVR can be performed with low operative mortality and satisfactory long-term outcomes.
- The procedure demonstrates significant regression of left ventricular mass, improving cardiac function.
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